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Degradation of the cyclin-dependent kinase inhibitor KRP1 is regulated by two different ubiquitin E3 ligases

✍ Scribed by Hong Ren; Aaron Santner; Juan Carlos del Pozo; James A. H. Murray; Mark Estelle

Book ID: 110867844
Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 580 KB
Volume: 53
Category: Article
ISSN: 0960-7412
DOI: 10.1111/j.1365-313x.2007.03370.x

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## Abstract Smooth muscle cells (SMC) play a central role in common vascular pathologies such as atherosclerosis and restenosis. Understanding the molecular regulation of SMC proliferation at a transcriptional level may provide important clues for the targeted control of vascular hyperplasia. We re