✦ LIBER ✦

Degenerate T-Cell Receptor Recognition, Autoreactive Cells, and the Autoimmune Response in Multiple Sclerosis

✍ Scribed by Markovic-Plese, S.

Book ID: 118736184
Publisher: SAGE Publications
Year: 2009
Tongue: English
Weight: 383 KB
Volume: 15
Category: Article
ISSN: 1073-8584
DOI: 10.1177/1073858409332404

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Degenerate TCR recognition and dual DR2

Degenerate TCR recognition and dual DR2 restriction of autoreactive T cells: Implications for the initiation of the autoimmune response in multiple sclerosis

✍ Xin Zhang; Yunan Tang; Danuta Sujkowska; Jinzhao Wang; Vinod Ramgolam; Mireia So 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 456 KB 👁 1 views

## Abstract TCR degeneracy may facilitate self‐reactive T cell activation and the initiation of an autoimmune response in multiple sclerosis (MS). MHC class II alleles of the DR2 haplotype DR2a (DRB5\*0101) and DR2b (DRB1\*1501) are associated with an increased risk for MS in Caucasian populations.

Molecular mimicry and multiple sclerosis

Molecular mimicry and multiple sclerosis: Degenerate T-cell recognition and the induction of autoimmunity

✍ Bruno Gran; Bernhard Hemmer; Marco Vergelli; Henry F. McFarland; Roland Martin 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 365 KB 👁 3 views

Cellular and Humoral Immune Responses Ag

Cellular and Humoral Immune Responses Against Autoreactive T cells in Multiple Sclerosis Patients After T cell Vaccination

✍ Guy Hermans; Ulrike Denzer; Ansgar Lohse; Jef Raus; Piet Stinissen 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 307 KB

T cells in multiple sclerosis and experi

T cells in multiple sclerosis and experimental autoimmune encephalomyelitis

✍ J. M. Fletcher; S. J. Lalor; C. M. Sweeney; N. Tubridy; K. H. G. Mills 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 529 KB

T helper cell differentiation in multipl

T helper cell differentiation in multiple sclerosis and autoimmunity

✍ Roland Martin; Nancy H Ruddle; Stephen Reingold; David A Hafler 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 128 KB

n experimental allergic encephalomyelitis (EAE), an animal model for multiple sclerosis (MS), T helper 1 (Th1)/Th2 immunological effector pathways are altered. Neuropathological findings and results from MS treatment trials suggest that our view of MS and other putative autoimmune diseases and their

Mast cells are required for optimal auto

Mast cells are required for optimal autoreactive T cell responses in a murine model of multiple sclerosis

✍ Gregory D. Gregory; Michaela Robbie-Ryan; Virginia H. Secor; Joseph J. Sabatino 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 324 KB 👁 1 views

## Abstract Once considered to be of sole importance in allergy and parasitic infections, the role of mast cells in other pathologic and protective immune responses is becoming increasingly evident. We previously demonstrated that mast cells contribute to the severity of EAE, the rodent model of mu