Loss of heterozygosity on chromosome arm
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Keltouma Driouch; Françoise Dorion-Bonnet; Marianne Briffod; Marie-Hélène Champè
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Article
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1997
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John Wiley and Sons
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English
β 111 KB
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One of the main genetic abnormalities associated with breast carcinogenesis is the loss of genetic material from chromosome arm 16q. Different groups have identified two regions (16q22.1 and 16q24-ter) that are frequently deleted in primary tumors, suggesting the presence of tumor suppressor genes i