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Defective Interfering DNAs of Plant Viruses

✍ Scribed by Patil, Basavaprabhu L.; Dasgupta, Indranil

Book ID
121691098
Publisher
Taylor and Francis Group
Year
2006
Tongue
English
Weight
622 KB
Volume
25
Category
Article
ISSN
0735-2689

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## Abstract Defective interfering (DI) virus is simply defined as a spontaneously generated virus mutant from which a critical portion of the virus genome has been deleted. At least one essential gene of the virus is deleted, either in its entirety, or sufficiently to make it non‐functional. The re

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Defective-interfering (DI) viruses arise spontaneously by deletion mutations. The shortened genomes of the DI particles cannot replicate unless they coinfect a cell with a wild-type virus. Upon coinfection, the DI genome replicates more quickly and outcompetes the wild type. The coinfected cell prod