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Defective expression of transforming growth factor β type II receptor (TGFBR2) in the large cell variant of non-small cell lung carcinoma

✍ Scribed by Xu, Ji-Bin; Bao, Yang; Liu, Xiaohong; Liu, Yanling; Huang, Shengdong; Wang, Jiu-Cun

Book ID
119319666
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
559 KB
Volume
58
Category
Article
ISSN
0169-5002

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Novel microdeletion in the transforming growth factor β type II receptor gene is associated with giant and large cell variants of nonsmall cell lung carcinoma
✍ Jiu-Cun Wang; Cheng-Chang Su; Ji-Bin Xu; Le-Zhen Chen; Xiao-Hua Hu; Gui-Ying Wan 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 386 KB 👁 1 views

## Abstract Mutations in the tumor suppressor gene transforming growth factor β (TGFB) Type II receptor (__TGFBR2__) are frequently found in many cancers with microsatellite instability, but are less common in lung cancer. In the present study, we looked for mutations in __TGFBR2__ in nonsmall cell