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Inactivation of the transforming growth factor β type II receptor in human small cell lung cancer cell lines

✍ Scribed by Hougaard, S; Nørgaard, P; Abrahamsen, N; Moses, H L; Spang-Thomsen, M; Skovgaard Poulsen, H

Book ID
110001025
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
468 KB
Volume
79
Category
Article
ISSN
0007-0920

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Retinoblastoma cells are resistant to transforming growth factor-b (TGF-b) activity due to the absence of TGF-b binding. To further elucidate the mechanism of TGF-b resistance, we studied the expression of the TGF-b receptors and SMADs by using the Y79 and WERI-Rb-1 retinoblastoma cell lines. Bindin