Defective Double-Strand DNA Break Repair and V(D) J Recombination In Patients With Common Variable Immune Deficiency
β Scribed by Ahn, S.; Kozlov, M.; Cortes, P.; Cunningham-Rundles, C.
- Book ID
- 119281418
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 44 KB
- Volume
- 123
- Category
- Article
- ISSN
- 1097-6825
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
the rearrangement process through the recognition of and Jean-Pierre de Villartay\* the RSS and the introduction of a DNA double-strand \* De Β΄veloppement Normal et Pathologique break (dsb) at the border of the heptamer (Schatz et du Syste `me Immunitaire al., 1989; Oettinger et al., 1990). The subs
The end-joining pathway of DNA double-strand break (DSB) repair is necessary for proper V(D)J recombination and repair of DSB caused by ionizing radiation. This DNA repair pathway can either use short stretches of (micro)homology near the DNA ends or use no homology at all (direct end-joining). We d