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Defective B-cell and regulatory T-cell function in Wiskott-Aldrich syndrome

✍ Scribed by Y. L. Lau; B. M. Jones; L. C. K. Low; S. N. Wong; N. K. Leung


Book ID
105413835
Publisher
Springer
Year
1992
Tongue
English
Weight
426 KB
Volume
151
Category
Article
ISSN
0340-6997

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The Wiskott-Aldrich syndrome (WAS) is a rare X-linked recessive disorder characterized by eczema, thrombocytopenia, and immunodeficiency. An allelic variant of the disease is characterized by isolated thrombocytopenia (XLT). The gene responsible for WAS/XLT (WASP) encodes for a 502 amino acid protei