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Decumbenone C, a new cytotoxic decaline derivative from the marine fungusAspergillus sulphureusKMM 4640

✍ Scribed by Olesya I. Zhuravleva, Shamil Sh. Afiyatullov…


Book ID
120958779
Publisher
Springer
Year
2012
Tongue
English
Weight
455 KB
Volume
35
Category
Article
ISSN
0253-6269

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✍ Véronique Ledroit; Cécile Debitus; Catherine Lavaud; Georges Massiot 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 125 KB

The ethanolic extract of the sponge Jaspis sp. collected in Vanuatu showed cytotoxicity against KB tumour cells (IC 95 =10 mg/ml). A bioassay-guided fractionation led to the isolation of two new cytotoxic sphingosine derivatives, jaspine A and jaspine B. Structures were elucidated by spectroscopic m