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Decreased unscheduled DNA synthesis in nondividing aged WI38 cells

โœ Scribed by P.D. Bowman; R.L. Meek; C.W. Daniel


Book ID
119024815
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
608 KB
Volume
5
Category
Article
ISSN
0047-6374

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Bromodeoxyuridine-selected nondividing senescent WI-38 cells were stimulated to synthesize DNA, as evidenced by incorporation of [3H]thymidine into nuclei of senescent cells, after infection with simian virus 40 (SV40). Cellular DNA synthesis was confirmed by DNA-DNA hybridization experiments and th

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