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Decreased binding of heparin to antithrombin following the interaction between antithrombin and thrombin

✍ Scribed by Anne-Sofie Carlström; Kerstin Liedén; Ingemar Björk


Book ID
119033554
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
853 KB
Volume
11
Category
Article
ISSN
0049-3848

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Nonspecific electrostatic binding charac
✍ Emek Seyrek; Paul L. Dubin; Jens Henriksen 📂 Article 📅 2007 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 585 KB

## Abstract We evaluated the role of nonspecific electrostatic binding in the interaction of antithrombin (AT) with heparin (Hp), a paradigmatic protein‐glycosaminoglycan (GAG) system. To do so, we obtained the ionic‐strength dependence of the binding constant, since a common feature in protein‐pol