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Synthesis of heparin-sepharoses and their binding with thrombin and antithrombin-heparin cofactor

โœ Scribed by I. Danishefsky; F. Tzeng; M. Ahrens; S. Klein

Book ID
119033449
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
829 KB
Volume
8
Category
Article
ISSN
0049-3848

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Preparation of three types of heparin-Se
Preparation of three types of heparin-Sepharose and their binding activities to thrombin and antithrombin III
โœ Miyuki Funahashi; Isamu Matsumoto; Nobuko Seno ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 634 KB

Three types of immobilized heparin, heparin-Sepharoses I, II, and III, were prepared to study the effect of the mode of the heparin attachment on the binding activities to thrombin and antithrombin III (AT-III). Heparin-Sepharose I was prepared by the coupling of the car-boxy1 groups of heparin with