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Decrease in oral bioavailability of cyclosporin A by coadministration of probucol in rats

โœ Scribed by Koh-ichi Sugimoto; Koh-ichi Sakamoto; Akio Fujimura

Book ID
117174772
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
516 KB
Volume
60
Category
Article
ISSN
0024-3205

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๐Ÿ“œ SIMILAR VOLUMES

Mechanism of decrease of oral bioavailab
Mechanism of decrease of oral bioavailability of cyclosporin A during immunotherapy upon coadministration of amphotericin B
โœ Junko Ishizaki; Satsuki Ito; Mingji Jin; Tsutomu Shimada; Tamae Ishigaki; Yukiko ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 153 KB

## Abstract The trough level of blood concentration of cyclosporin A (CyA) in a patient receiving immunotherapy was observed to decrease following coadministration of amphotericin B (AMB). This clinical observation was confirmed experimentally in Wistar rats intravenously given AMB (1.5 or 3.0โ€‰mg/k