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Marked decrease of cyclosporin bioavailability caused by coadministration of ginkgo and onion in rats

✍ Scribed by C.Y. Yang; P.D.L. Chao; Y.C. Hou; S.Y. Tsai; K.C. Wen; S.L. Hsiu


Book ID
116461639
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
154 KB
Volume
44
Category
Article
ISSN
0278-6915

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Isolated rat hepatocyte couplets were used to study the effect of S-adenosyl-L methionine (SAMe) treatment on disruption of canalicular function caused by cyclosporin A (CyA). Canalicular function was assessed by counting the percentage of couplets that were able to accumulate the fluorescent cholep