Decomposition of p-aminosalicylic acid in the solid state
โ Scribed by J. T. Carstensen; Pakdee Pothisiri
- Publisher
- John Wiley and Sons
- Year
- 1975
- Tongue
- English
- Weight
- 727 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A series of alkoxyfuroic acids with alkyl lengths of n = 8-18 was synthesized, and the solid-state decomposition was studied. Bawn kinetics were adhered to, and the solid and liquid decomposition rate constants were established; they followed an Arrhenius relationship well, with energy of activation
Sir P. C. Ray Fellow's Laboratory, University b l l e g e of Science and Technology. Calcutta. t The authon are indebted to Dr. S. K.' Muker'ee Herbarium Curator, Royal. Botanic Garden. Sibpur. hicutts. for suggtwionn on botanlcnl matter.
suggested that product inhibition (including cross-product inhibition) of drug biotransformation processes may be due to an interaction of the inhibitory agents with cytochrome P-450 (8,14). Specifically, a competition between the hydroxylated metabolite and the drug for binding sites on cytochrome