De novo protein design. I. in search of stability and specificity
โ Scribed by Patrice Koehl; Michael Levitt
- Book ID
- 115629733
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 437 KB
- Volume
- 293
- Category
- Article
- ISSN
- 0022-2836
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The solution to the protein folding problem lies in defining the relative energetic contributions of short-range and long-range interactions. In other words, the tendency of a stretch of amino acids to adopt a final secondary structural fold is context dependent. Our approach to this problem is to a
## Abstract Significant progress has been made in recent years toward creating interesting, unique, and in some cases, predictable oligopeptoid/polypeptoid secondary, tertiary, and in one case, quaternary structures. This article describes this progress, identifies a few of the many remaining chall