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De novo mutations in familial adenomatous polyposis (FAP)

✍ Scribed by Ripa, Rasmus; Bisgaard, Marie Luise; Bülow, Steffen; Nielsen, Finn Cilius

Book ID
110025274
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
159 KB
Volume
10
Category
Article
ISSN
1018-4813

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## Development of one hundred or more adenomas in the colon and rectum is diagnostic for the dominantly inherited, autosomal disease Familial Adenomatous Polyposis (FAP). It is possible to identify a mutation in the Adenomatous Polyposis Coli (APC) gene in approximately 80% of the patients, and alm