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DDX3 regulates DNA damage-induced apoptosis and p53 stabilization

✍ Scribed by Sun, Mianen; Zhou, Tong; Jonasch, Eric; Jope, Richard S.


Book ID
120268656
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
929 KB
Volume
1833
Category
Article
ISSN
0167-4889

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or overexpression of the Max-Planck-Institute for Biochemistry negative regulator Mdm2 (Freedman et al., 1999). For Am Klopferspitz 18a those tumors that retain functional p53 but have ampli-D 82152 Martinsried fication of Mdm2, therapeutic strategies have been Germany developed to inhibit Mdm2, whe