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D2 dopamine receptors in the rat prefrontal cortex: characterization and alteration by stress

โœ Scribed by A. John MacLennan; M.A. Pelleymounter; Stella Atmadja; Alexander Jakubovic; Steven F. Maier; H.C. Fibiger


Book ID
115799954
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
648 KB
Volume
477
Category
Article
ISSN
0006-8993

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Chronic haloperidol administration incre
โœ A. John MacLennan; Stella Atmadja; Nancy Lee; H. C. Fibiger ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Springer ๐ŸŒ English โš– 299 KB

Rats received haloperidol (1.3-1.5 mg/kg/day) via their drinking water for 21 weeks. At the end of this period the density of D2 dopamine receptors and their affinity for [3H]-spiperone were measured in the striatum and medial prefrontal cortex. The chronic haloperidol treatment increased the densit