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No change in neostriatal D-2 dopamine receptors after NMDA lesions of rat prefrontal cortex

✍ Scribed by Sarah Bridge; MacDonald J. Christie; Philip M. Beart


Book ID
113220943
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
353 KB
Volume
24
Category
Article
ISSN
0091-3057

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Rats received haloperidol (1.3-1.5 mg/kg/day) via their drinking water for 21 weeks. At the end of this period the density of D2 dopamine receptors and their affinity for [3H]-spiperone were measured in the striatum and medial prefrontal cortex. The chronic haloperidol treatment increased the densit