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d-Glucose- and d-mannose-based antimetabolites. Part 2. Facile synthesis of 2-deoxy-2-halo-d-glucoses and -d-mannoses

✍ Scribed by Izabela Fokt; Slawomir Szymanski; Stanislaw Skora; Marcin Cybulski; Timothy Madden; Waldemar Priebe


Book ID
108080647
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
335 KB
Volume
344
Category
Article
ISSN
0008-6215

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Labeled 2-deoxy-D-glucose analogs. 18F-l
✍ T. Ido; C-N. Wan; V. Casella; J. S. Fowler; A. P. Wolf; M. Reivich; D. E. Kuhl πŸ“‚ Article πŸ“… 1978 πŸ› John Wiley and Sons 🌐 French βš– 337 KB πŸ‘ 1 views

## Abstract A convenient method for the synthesis of ^18^F‐2‐deoxy‐2‐fluoro‐D‐glucose (4) and ^18^F‐2‐deoxy‐2‐fluoro‐D‐mannose (8) by the direct fluorination of 3,4,6‐tri‐0‐acetyl‐D‐glucal with ^18^F‐F~2~ is described. ^14^C‐2‐deoxy‐2‐fluoro‐D‐glucose has been synthesized from ^14^C‐3,4,6‐tri‐0‐ace