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Cytotoxic and proapoptotic activity of ent-16β-17α-dihydroxykaurane on human mammary carcinoma cell line MCF-7

✍ Scribed by Alvaro Morales; Pedro Pérez; Raifish Mendoza; Reinaldo Compagnone; Alírica I. Suarez; Francisco Arvelo; José Luis Ramírez; Iván Galindo-Castro


Book ID
116333265
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
205 KB
Volume
218
Category
Article
ISSN
0304-3835

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Cytofluorimetric and reverse-transcription polymerase chain reaction (RT-PCR) analysis showed that adriamycinresistant (ADR R ), but not sensitive (WT), MCF-7 human mammary carcinoma cell lines express a4b1 and a5b1 integrins. ADR R cells adhere to fibronectin (FN), and only a5b1 is involved in cell