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Cytotoxic and non-genotoxic effects of arecoline on human buccal fibroblasts in vitro

โœ Scribed by Yu-Chao Chang; Kuo-Wei Tai; Min-Hsiung Cheng; Lin Shin-Shen Chou; Ming-Yung Chou

Book ID
111253734
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
414 KB
Volume
27
Category
Article
ISSN
0904-2512

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Cytotoxic and cytostatic effects of arec
Cytotoxic and cytostatic effects of arecoline and sodium nitrite on human cells in vitro
โœ K. K. Wary; R. N. Sharan ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 488 KB ๐Ÿ‘ 1 views

Arecoline, an active alkaloid of Areca catechu L., and sodium nitrite, a food additive, are highly cytotoxic and cytostatic on the Hep 2 cell line when administered in an acidic environment (pH 4.2) in the presence of S-9 mixture. Hep 2 cells (10(6)) were treated with either 0.145, 0.725 or 1.449 mM