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Cytosine arabinoside cerebrospinal fluid kinetics

✍ Scribed by Zimm, Solomon; Collins, Jerry M; Miser, James; Chatterji, Dulal; Poplack, David G

Book ID: 109843365
Publisher: Nature Publishing Group
Year: 1984
Tongue: English
Weight: 368 KB
Volume: 35
Category: Article
ISSN: 0009-9236
DOI: 10.1038/clpt.1984.120

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Subcutaneous bolus administration of cytosine arabinoside (Ara-C) has been used as an alternative to continuous intravenous infusion. However, the pharmacokinetics of subcutaneous bolus Ara-C have not been satisfactorily documented in man. The plasma concentrations of Ara-C were therefore compared f