## Abstract Nitric oxide (NO) from astrocytes is one of the signalers used by the brain's extensive glial‐neuronal‐vascular network, but its excessive production by pro‐inflammatory cytokine‐stimulated glial cells can be cytodestructive. Here, we show how three pro‐inflammatory cytokines (IL‐1β, TN
✦ LIBER ✦
Cytokines stimulate expression of inducible nitric oxide synthase in DLD-1 human adenocarcinoma cells by activating poly(A) polymerase
✍ Scribed by K. G. K. Murthy; C. Szabó; A. L. Salzman
- Publisher
- SP Birkhäuser Verlag Basel
- Year
- 2004
- Tongue
- English
- Weight
- 144 KB
- Volume
- 53
- Category
- Article
- ISSN
- 1420-908X
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## Abstract Since NO production by NOS‐2 made by astrocytes activated by proinflammatory cytokines contributes to the killing of neurons in variously damaged human brains, knowing the mechanisms responsible for NOS‐2 expression should contribute to developing effective therapeutics. The expression
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