𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Cytokines, Jaks, Stats, health and disease

✍ Scribed by Brown, M. P.


Book ID
109001123
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
605 KB
Volume
29
Category
Article
ISSN
0004-8291

No coin nor oath required. For personal study only.


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JAK/STAT signaling by cytokine receptors
✍ Kathleen D Liu; Sarah L Gaffen; Mark A Goldsmith πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 English βš– 712 KB

The JAK/STAT pathway is recognized as one of the major mechanisms by which cytokine receptors transduce intracellular signals. This system is regulated at multiple levels, including JAK activation, nuclear trafficking of STAT factors, and negative feedback loops. Gene deletion studies have implicate