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Cytokine responses in acute and persistent human parvovirus B19 infection

✍ Scribed by A. Isa; A. Lundqvist; A. Lindblom; T. Tolfvenstam; K. Broliden


Book ID
110090517
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
226 KB
Volume
147
Category
Article
ISSN
0009-9104

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## Abstract A subset of parvovirus B19 (B19) infected patients retains the infection for years, as defined by detection of B19 DNA in bone marrow. Thus far, analysis of B19‐specific humoral immune responses and viral genome variations has not revealed a mechanism for the absent viral clearance. In

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Background and Procedure. The frequency and clinical importance of parvovirus B19 infection were studied in children investigated or treated for various malignancies and cytopenias. Results. B19 infection was thus demonstrated in six out of 53 unselected children with malignancies by bone marrow exa