Cytogenetic subgroups in uterine leiomyomas
โ Scribed by Aurelia M. Meloni; Urvashi Surti; Avery A. Sandberg
- Book ID
- 119105091
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 58 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0165-4608
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Our cytogenetic findings in 175 uterine leiomyomas revealed 52 tumors with clonal chromosome abnormalities, eight of which did not belong to any well-delineated cytogenetic abnormal subgroup. However, an interstitial deletion of the long arm of chromosome 3 was found, as the sole chromosome abnormal
Uterine leiomyoma-a benign smooth muscle tumor-has recently been found t o contain tumor-specific chromosome aberrations. Although only normal karyotypes were detected in 50 t o 80% of cytogenetically investigated tumors, 104 leiomyomas with karyotypic aberrations have already been reported. At leas