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A new cytogenetic subgroup in uterine leiomyoma is characterized by a deletion of the long arm of chromosome 3

✍ Scribed by Paola Dal Cin; Philippe Moerman; Jan Deprest; Ivo Brosens; Herman Van Den Berghe


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
129 KB
Volume
13
Category
Article
ISSN
1045-2257

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✦ Synopsis


Our cytogenetic findings in 175 uterine leiomyomas revealed 52 tumors with clonal chromosome abnormalities, eight of which did not belong to any well-delineated cytogenetic abnormal subgroup. However, an interstitial deletion of the long arm of chromosome 3 was found, as the sole chromosome abnormality, in three cases. We believe that this involvement of 3q is significant enough to consider it as a new cytogenetic subgroup of uterine leiomyoma. Genes Chromosom Cancer 13:219-220 (1995). 0 1995 Wiley-Lia. Inc.


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