Cytogenetic studies of thyroid hyperplasias and adenomas have shown that besides cases with an apparently normal karyotype different groups of cytogenetic abnormalities exin Herein we describe the cytogenetic analyses o f two benign thyroid tumors with deletions of the short arm of chromosome 2. A s
A new cytogenetic subgroup in uterine leiomyoma is characterized by a deletion of the long arm of chromosome 3
β Scribed by Paola Dal Cin; Philippe Moerman; Jan Deprest; Ivo Brosens; Herman Van Den Berghe
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 129 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1045-2257
No coin nor oath required. For personal study only.
β¦ Synopsis
Our cytogenetic findings in 175 uterine leiomyomas revealed 52 tumors with clonal chromosome abnormalities, eight of which did not belong to any well-delineated cytogenetic abnormal subgroup. However, an interstitial deletion of the long arm of chromosome 3 was found, as the sole chromosome abnormality, in three cases. We believe that this involvement of 3q is significant enough to consider it as a new cytogenetic subgroup of uterine leiomyoma. Genes Chromosom Cancer 13:219-220 (1995). 0 1995 Wiley-Lia. Inc.
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Since the first patient with partial deletion of the long arm of chromosome 10 was described in 1978, another 23 cases have been reported, with the breakpoint ranging from 10q23.3-26.2. To contribute further to the delineation of the monosomy 10qter syndrome, we describe a female child who, at age 3
We encountered a 67-year-old female with chronic neutrophilic leukemia (CNL). Cytogenetic study showed she had a deletion in the long arm of chromosome 20. This finding indicates that CNL, in this case, is a clonal disorder. Most CNL patients have normal karyotypes, and only four patients with cytog
## Abstract Interstitial deletions of the long arm of chromosome 3 are uncommon. Most cases are related to the blepharophimosisβptosisβepicanthus inversus syndrome (BPES), which is mapped to 3q23. We report on a case with a de novo chromosomal deletion of 3q23 and 3q25. We review the literature on