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Deletions of the short arm of chromosome 2 characterize a new cytogenetic subgroup of benign thyroid tumors

✍ Scribed by Gazanfer Belge; Sandra Bruckmann; Brita Thode; Sabine Bartnitzke; Jörn Bullerdiek


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
209 KB
Volume
16
Category
Article
ISSN
1045-2257

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✦ Synopsis


Cytogenetic studies of thyroid hyperplasias and adenomas have shown that besides cases with an apparently normal karyotype different groups of cytogenetic abnormalities exin Herein we describe the cytogenetic analyses o f two benign thyroid tumors with deletions of the short arm of chromosome 2. A similar case has been described previously. Besides the previously well-established subgroups, alterations of chromosome 2 may thus characterize a new cytogenetic subgroup of benign thyroid tumors.


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Small terminal deletions of the long arm
✍ Fisher, Andrew M. ;Ellis, Katrina H. ;Browne, Caroline E. ;Barber, John C. K. ;B 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 452 KB 👁 1 views

We report on 2 girls with small de novo terminal deletions of the long arm of chromosome 2 and breakpoints within q37. Four cases with similar or more extensive deletions have been previously reported in full. Hypotonia and psychomotor retardation were the only manifestations common to all 6 cases.

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