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Cytogenetic study of breast cancer: Clinicopathologic significance of homogeneously staining regions in 84 patients

✍ Scribed by Brigitte Zafrani; Michèle Gerbault-Seureau; Véronique Mosseri; Bernard Dutrillaux

Book ID
119023957
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
541 KB
Volume
23
Category
Article
ISSN
1532-8392

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Identification of amplified DNA sequence
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A modified comparative genomic hybridization (mCGH) technique was used t o identify and map amplified DNA sequences in six homogeneously staining regions (hsr) from three primary breast carcinomas. Five different chromosomal regions and bands were identified as sites of amplification: 8p I, I7q2 I.