Cytogenetic studies on 19 papillary thyroid carcinomas
β Scribed by Patrick Antonini; Anne-Marie Venuat; Bernard Caillou; Roland Berger; Martin Schlumberger; Alain Bernheim; Claude Parmentier
- Book ID
- 102845424
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 528 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1045-2257
No coin nor oath required. For personal study only.
β¦ Synopsis
Short-term cultures from I9 papillary thyroid adenocarcinomas revealed clonal numerical and/or structural chromosomal changes in I3 tumors, nonclonal abnormalities in one tumor, and only normal karyotypes in five tumors. Clonal abnormalities of chromosome 10 were present in three tumors, two of which had the translocation t(7; IO)(q35;q2 I). Numerical abnormalities of chromosome I 7 were detected in two tumors. Genes Chrom Cancer 5:206-2 I / ( / 992). @ 1992 Wiley-Lirs. Inc.
π SIMILAR VOLUMES
Chromosome studies performed on 3 I papillary thyroid carcinomas (PTCs) revealed clonal numerical and structural abnormalities in I2 tumors. The numerical clonal aberrations found were trisomy 2, trisomy 7, and loss of the Y chromosome. A nonrandom telomeric association, tas( I 5; I6)(p I );p I 3),
A combined cytogenetic and molecular analysis was performed on I I cases of papillary thyroid carcinoma. A simple karyotypic abnormality was detected in five tumors, whereas six had no apparent chromosome change. In four of five rearranged cases the presence of a specific chromosomal abnormality inv