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Cytogenetic, morphologic, and clinical correlations in acute nonlymphocytic leukemia with t(8q−;21q+)


Book ID
119102472
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
183 KB
Volume
2
Category
Article
ISSN
0165-4608

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Homozygosity for 8pter→q22 in acute myel
✍ Dr. Roland Berger 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 293 KB

A case of acute nonlymphocytic leukemia with homozygosity for the chromosome segment 8pter-4q22 is reported. A t(8;2 l)(q22;q22) translocation was associated with duplication of the derivative chromosome 8q-and absence of the normal chromosome 8. These rearrangements also yielded hemizygosity for 8q