A newborn with Down syndrome was noted on the 1st day of life to have an elevated white blood cell count of 79,900/mm3 with 62% lymphoblasts and a platelet count of 61 ,000/mm3, consistent with either transient myeloproliferative disorder of Down syndrome (TMD) or acute leukemia. Karyotype analysis
Cytogenetic features of 5q deletion and 5q− syndrome in myelodysplastic syndrome in Korea; marker chromosomes proved to be chromosome 5 with interstitial deletion by fluorescence in situ hybridization
✍ Scribed by Hye Ryun Lee; Bora Oh; Dae Sik Hong; Dae Young Zang; Hwi-Joong Yoon; Hyeoung Joon Kim; Inho Kim; Jae-Sook Ahn; June-Won Cheong; Kyung-A Lee; Kyung Sam Cho; Mark Hong Lee; Soo-Mee Bang; Tae Young Kim; Yeo-Min Yun; Yoo Hong Min; You Kyoung Lee; Dong Soon Lee
- Book ID
- 119211576
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 431 KB
- Volume
- 203
- Category
- Article
- ISSN
- 0165-4608
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## Abstract Isolated deletions of the long arm of chromosome 5, del(5q), are observed in 10% of myelodysplastic syndromes (MDS) and are associated with a more favorable prognosis, although the clinical course varies considerably. If one or more additional chromosomal aberrations are present, this c
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