A cytogenetic study of pleural effusions (PE) containing metastatic or invasive tumor cells from I I patients with non-small cell lung cancer (NSCLC) (3 squamous cell carcinomas [SQC] and 8 adenocarcinomas [ADC] including I giant cell variant) was performed t o identify non-random chromosome abnorma
Cytogenetic abnormalities in non small cell lung cancer
β Scribed by R.E. Lukeis; L. Irving; S. Hasthorpe; D. Ball; O.M. Garson
- Book ID
- 119104376
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 67 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0165-4608
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Cytogenetic analysis of ten primary non-small cell lung carcinomas (NSCLC), including five adenocarcinomas (ADC), three squamous cell (SQC), and two large cell (LCC) carcinomas has been carried out in an attempt to determine karyotype changes involved in the early stage of disease. The tumors were a
## Abstract ## Background Interphase cytogenetics by fluorescence in situ hybridization (FISH) has been demonstrated to be a valuable diagnostic tool in effusions from patients with solid tumors. As the next step, we investigated whether certain patterns of numeric aberrations in malignant effusio