Chromosome abnormalities in non small cell lung carcinoma
✍ Scribed by Franck Viguié; Valérie Drouin; Jeanne Marie Bréchot; Frédérique Capron; Sylvie Ramond; Bernard Debesse; Jacques Rochemaure
- Book ID
- 113253512
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 85 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0165-4608
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📜 SIMILAR VOLUMES
## 1. R.) Cytogenetic analysis was performed on I 6 primary tumors, 2 effusions, and 3 cell lines from 2 I patients with non-small cell lung cancer (NSCLC). In 20 patients specimens were obtained prior t o initiating cytotoxic therapy. Extensive clonal chromosome alterations were found in all cases
Several somatic genetic alterations have been described in non-small-cell lung carcinomas (NSCLC). Recurrent chromosomal deletions have suggested the presence of tumor-suppressor genes specifically involved in lung carcinogenesis. For one of these, 2 non-overlapping regions have been proposed on the