𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Cytochrome P450 structures and their substrate interactions

✍ Scribed by David F.V. Lewis; Yuko Ito; Peter S. Goldfarb

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
151 KB
Volume
66
Category
Article
ISSN
0272-4391

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Toxic alkaloids and their interaction wi
Toxic alkaloids and their interaction with microsomal cytochrome P-450 in vitro
✍ A. Peeples; R. R. Dalvi πŸ“‚ Article πŸ“… 1982 πŸ› John Wiley and Sons 🌐 English βš– 304 KB

## Abstract Studies on the binding spectra of certain alkaloids with rat liver microsomes revealed that brucine, scopolamine and strychnine are type I compounds, whereas boldine, emetine, nicotine, reserpine and sanguinarine show type II binding. In contrast, colchicine and solanine failed to produ

Mechanisms of cytochrome P450 substrate
Mechanisms of cytochrome P450 substrate oxidation: MiniReview
✍ F. Peter Guengerich πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 287 KB

## Abstract Cytochrome P450 (P450) enzymes catalyze a variety of oxidation and some reduction reactions, collectively involving thousands of substrates. A general chemical mechanism can be used to rationalize most of the oxidations and involves a perfenyl intermediate (FeO^3+^) and odd‐electron che

Structure and Chemistry of Cytochrome P4
Structure and Chemistry of Cytochrome P450
✍ Ilia G. Denisov; Thomas M. Makris; Stephen G. Sligar; Ilme Schlichting πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons βš– 8 KB

## Abstract For Abstract see ChemInform Abstract in Full Text.

COMPACT: a structural approach to the mo
COMPACT: a structural approach to the modelling of cytochromes P450 and their interactions with xenobiotics
✍ David Fβ€ŠV Lewis πŸ“‚ Article πŸ“… 2001 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 152 KB

## Abstract An overview of the COMPACT method for evaluating potential toxicity mediated by cytochrome P450 enzymes is presented. Particular aspects of P450s are described, together with details of QSARs and homology modelling of mammalian P450s associated with foreign compound metabolism. Β© 2001