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Cytochrome P450-catalyzed insertion of carbenoids into N–H bonds

✍ Scribed by Wang, Z. Jane ;Peck, Nicole E. ;Renata, Hans ;Arnold, Frances H.


Book ID
127033832
Publisher
The Royal Society of Chemistry
Year
2014
Tongue
English
Weight
342 KB
Volume
5
Category
Article
ISSN
2041-6520

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Mechanism of metal-carbenoid insertion i
✍ Yannick Landais; Liliana Parra-Rapado; Denis Planchenault; Valéry Weber 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 286 KB

Kinetic investigations on the insertion of metal-carbenoid intermediates into the Si-H bond have been carried out. A kinetic isotope effect of 1.5 was found and the plot of log kx/krt vs cr for the reaction of arylsilanes with EDA, gave a straight line with p =-0.31. It was thus concluded that the i