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Cytochrome P-450 suggestions as to the structure and mechanism of action

✍ Scribed by H. A. O. Hill; A. Röder; R. J. P. Williams

Publisher
Springer
Year
1970
Tongue
English
Weight
450 KB
Volume
57
Category
Article
ISSN
0028-1042

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COMPACT: a structural approach to the modelling of cytochromes P450 and their interactions with xenobiotics
✍ David F V Lewis 📂 Article 📅 2001 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 152 KB

## Abstract An overview of the COMPACT method for evaluating potential toxicity mediated by cytochrome P450 enzymes is presented. Particular aspects of P450s are described, together with details of QSARs and homology modelling of mammalian P450s associated with foreign compound metabolism. © 2001