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Cytochrome P-450-catalyzed stereoselective epoxidation at the K region of benz[a]anthracene and benzo[a]pyrene

โœ Scribed by Shen K. Yang; Pei-Lu Chiu

Book ID
115706410
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
618 KB
Volume
240
Category
Article
ISSN
0003-9861

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## Abstract Female Spragueโ€Dawley rats were given a subcutaneous injection of the parent hydrocarbon or its Kโ€region epoxide in 0.1 ml sesame oil on alternate days to a total of 30 doses and observed for sarcoma at the site of injection for 275 days. The parent compounds, benzo(a)__pyrene (0.2 ฮผmol