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CYP2D6Polymorphisms and Tamoxifen Metabolism: Clinical Relevance

✍ Scribed by Michaela J. Higgins; Vered Stearns


Book ID
107546724
Publisher
Current Science Inc.
Year
2010
Tongue
English
Weight
232 KB
Volume
12
Category
Article
ISSN
1523-3790

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CYP2D6 polymorphisms and the impact on t
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The cytochrome P450 2D6 (CYP2D6) is an enzyme known to metabolize a variety of xenobiotics and drugs. Inter-individual variation in the metabolic capacity of this enzyme has been extensively studied and associations with genotype have been established. Genetic polymorphisms have been grouped as nonf