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Cyclooxygenase-2/prostaglandin E2 pathway mediates icariside II induced apoptosis in human PC-3 prostate cancer cells

โœ Scribed by Keun-Sung Lee; Hyo-Jeong Lee; Kwang Seok Ahn; Sun-Hee Kim; Dongwoo Nam; Dae Keun Kim; Do-Young Choi; Kyoo-Seok Ahn; Junxuan Lu; Sung-Hoon Kim

Book ID
116335166
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
1023 KB
Volume
280
Category
Article
ISSN
0304-3835

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โœ Xingya Wang; Russell D. Klein ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 295 KB

Prostaglandin E 2 (PGE 2 ) has been shown to induce expression of vascular endothelial growth factor (VEGF) and other signaling molecules in several cancers. PGE 2 elicits its functions though four G-protein coupled membrane receptors (EP1-4). In this study, we investigated the role of EP receptors