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Cyclooxygenase-2 expression correlates with angiogenesis and apoptosis in gastric cancer tissue

✍ Scribed by Atsushi Tatsuguchi; Kazuhiro Matsui; Yoko Shinji; Katya Gudis; Taku Tsukui; Teruyuki Kishida; Yuh Fukuda; Yuichi Sugisaki; Akira Tokunaga; Takashi Tajiri; Choitsu Sakamoto


Book ID
116533667
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
321 KB
Volume
35
Category
Article
ISSN
1532-8392

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## Abstract ## Introduction The cyclooxygenase‐2 (COX‐2), responsible for the conversion of arachidonic acid into prostaglandin (PG) E2, is known to increase intracellular cAMP and estrogen production in malignant breast tissue. The aromatase enzyme complex is responsible for local production of e