Preparation of ฮฒ -alanine-3,3-D2 and โ2,
โ
Kazuhiko Hanai; Akio Kuwae
๐
Article
๐
1988
๐
John Wiley and Sons
๐
French
โ 263 KB
B -Alanine-3,3-d2 and -2,2,3,3-d4 were prepared via a five-step procedure from ethyl cyanoacetate. The procedure involves reduction of the starting material with lithium aluminum deuteride, followed by benzoylation of the amino alcohol obtained, oxidation of the benzoylated compound, hydrolysis of b