Cyclization of deprotonated 2-phenyl-1-t
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Hans-Joachim Breternitz; Ernst Schaumann; Gunadi Adiwidjaja
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Article
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1991
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Elsevier Science
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French
β 212 KB
## Deprotonation of 2-phenyl-1-tosylaziridine 1 with butyl lithium gives an anion that cyclizes to 4 by an intramolecular nucleophilic aromatic addition. Treatment of derivatives 5, 6 with a Grignard reagent produces aziridines 10, 11.