✦ LIBER ✦

Cyclization of deprotonated 2-phenyl-1-tosylaziridine. A surprising example of an intramolecular nucleophilic aromatic addition

✍ Scribed by Hans-Joachim Breternitz; Ernst Schaumann; Gunadi Adiwidjaja

Book ID: 104216093
Publisher: Elsevier Science
Year: 1991
Tongue: French
Weight: 212 KB
Volume: 32
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)79650-x

No coin nor oath required. For personal study only.

✦ Synopsis

Deprotonation of 2-phenyl-1-tosylaziridine

1 with butyl lithium gives an anion that cyclizes to 4 by an intramolecular nucleophilic aromatic addition. Treatment of derivatives 5, 6 with a Grignard reagent produces aziridines 10, 11.

📜 SIMILAR VOLUMES

Cyclization of 2-azidobenzophenones to 3

Cyclization of 2-azidobenzophenones to 3-phenylanthranils. Examples of an intramolecular 1,3-dipolar addition

✍ Hall, J. Herbert; Behr, Fred E.; Reed, Raymond L. 📂 Article 📅 1972 🏛 American Chemical Society 🌐 English ⚖ 809 KB

Unexpected formation of 4,4,6-trimethyl-

Unexpected formation of 4,4,6-trimethyl-2-oxo-1-phenyl-1,2,3,4-tetrahydropyridine-3-carbonitrile via Tandem Knoevenagel condensation-Michael addition-intramolecular cyclization

✍ A. A. Nikishin; V. D. Dyachenko; A. N. Chernega 📂 Article 📅 2009 🏛 SP MAIK Nauka/Interperiodica 🌐 English ⚖ 170 KB

ChemInform Abstract: Unexpected Formatio

ChemInform Abstract: Unexpected Formation of 4,4,6-Trimethyl-2-oxo-1-phenyl-1,2,3,4-tetrahydropyridine-3-carbonitrile via Tandem Knoevenagel Condensation—Michael Addition—Intramolecular Cyclization.

✍ A. A. Nikishin; V. D. Dyachenko; A. N. Chernega 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

ChemInform Abstract: Base-Induced Cycliz

ChemInform Abstract: Base-Induced Cyclization of 1-Benzyloxy-2,2,4,4-tetramethylpentan-3-ones: Intramolecular Nucleophilic Addition of an Anion of a Benzyl Ether to the Carbonyl Moiety Without the Wittig Rearrangement or Protophilic Decomposition.

✍ M. MATSUMOTO; N. WATANABE; A. ISHIKAWA; H. MURAKAMI 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB

Base-Induced Cyclization of 1-Benzyloxy-2,2,4,4-tetramethylpentan-3-ones: Intramolecular Nucleophilic Addition of an Anion of a Benzyl Ether to the Carbonyl Moiety Without the Wittig Rearrangement or Protophilic Decomposition. -Two combinations of base and solvent are found to be effective for the

ChemInform Abstract: Synthesis of Nitrog

ChemInform Abstract: Synthesis of Nitrogen Heterocycle-Fused 1,2,4-Benzothiadiazine-1,1-dioxide, Quinazolinone, and Pyrrolidinone Derivatives with a Guanidine Joint via Sequential aza-Wittig Reaction/Intramolecular NH-Addition Cyclization/Nucleophilic Substitution Ring Closure Methodology, Using Functionalized Carbodiimides as Key Intermediates.

✍ Shinsuke Hirota; Terumi Sakai; Nobuhide Kitamura; Keisuke Kubokawa; Noriki Kutsu 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 76 KB 👁 2 views

ChemInform Abstract: 1,2-Nucleophilic Ad

ChemInform Abstract: 1,2-Nucleophilic Addition on 2-Phenyl-3H-indol-3-one and 2-Phenyl-3-phenylimino-3H-indole and Their Corresponding 1-Oxides. An Attempt to Synthesize Water-Soluble Aminoxyls. Crystal Structure of 3-Ethoxycarbonyl-2,3,3a,4-tetrahydro-2,4-dioxo-3a-phenylisoxazolo [2,3-a]indole.

✍ Giampaolo Tommasi; Paolo Bruni; Lucedio Greci; Paolo Sgarabotto; Lara Righi 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB 👁 2 views