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Cyclin T1 stabilizes expression levels of HIV-1 Tat in cells

✍ Scribed by Kenichi Imai; Kaori Asamitsu; Ann Florence B. Victoriano; Marni E. Cueno; Koh Fujinaga; Takashi Okamoto

Book ID
111313289
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
398 KB
Volume
276
Category
Article
ISSN
1432-1327

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HIV-1 gene expression relies upon a complex machinery that is primarily controlled by two viral regulatory proteins, Tat and Rev. Rev is involved in regulating post-transcriptional events of HIV-1 gene expression. The Tat protein transactivates transcription from the HIV-1 5Ј long terminal repeat (L