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Cyclin-dependent kinase inhibitors, p21waf1/cip1 and p27kip1, are expressed site- and hair cycle-dependently in rat hair follicles

✍ Scribed by Mitsui, Shinichi; Ohuchi, Atsushi; Adachi-Yamada, Takashi; Hotta, Mitsuyuki; Tsuboi, Ryoji; Ogawa, Hideoki

Book ID: 119560788
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 241 KB
Volume: 25
Category: Article
ISSN: 0923-1811
DOI: 10.1016/s0923-1811(00)00132-8

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WAF1/Cip1/Sdi1 (p21) is the prototype of a family of proteins that inhibit cyclin-dependent kinases and regulate cell cycle progression in eukaryotic cells. In addition to normal cell cycle progression, p21 is involved in growth suppression mediated by p53 and transforming growth factor beta (TGFbet