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Cyclin D1b protein expression in breast cancer is independent of cyclin D1a and associated with poor disease outcome

✍ Scribed by Millar, E K A; Dean, J L; McNeil, C M; O'Toole, S A; Henshall, S M; Tran, T; Lin, J; Quong, A; Comstock, C E S; Witkiewicz, A


Book ID
109970929
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
621 KB
Volume
28
Category
Article
ISSN
0950-9232

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Background and Objectives: p27Kip1 is an inhibitor of cyclindependent kinases and is speculated to be a potential prognostic indicator in numerous human cancers. We investigated expression of p27Kip1 along with cyclin D1 in gastric cancer to estimate the clinical utility of p27Kip1. Methods: Immunoh