Cyclin D1 is a major positive regulator of the G 1 restriction point promoting inactivation of the retinoblastoma protein (RB). The cyclin D1 gene is rearranged, amplified and/or over-expressed in several human neoplasms. In the present series of 64 human breast carcinomas, cyclin D1 amplification (
CCND1amplification and cyclin D1 expression in breast cancer and their relation with proteomic subgroups and patient outcome
β Scribed by Somaia Elsheikh; Andrew R. Green; Mohammed A. Aleskandarany; Matthew Grainge; Claire E. Paish; Maryou B. K. Lambros; Jorge S. Reis-Filho; Ian O. Ellis
- Publisher
- Springer US
- Year
- 2007
- Tongue
- English
- Weight
- 340 KB
- Volume
- 109
- Category
- Article
- ISSN
- 0167-6806
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